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To learn more about the Department of Mechanical Engineering at the University of South Carolina, call or mail us at:
The University of South Carolina
Department of Mechanical Engineering
300 Main Street
Columbia, SC 29208
Ph 803.777.4185
Fax 803.777.0106
Maps:
USC campus
Columbia, SC
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Dr.
Tarek Shazly
Assistant
Professor
Diverse
interactions
between soft
tissues and
implanted
biomaterials
directly
influence
the success
or failure
of
therapeutic
interventions.
The nature,
time course
and extent
of governing
interactions
depend
strongly on
both the
tissues and
materials
involved in
a given
clinical
scenario.
Despite
extreme
variations
in tissue
surface
morphologies,
mechanics
and
chemistries,
these and
other
differences
are often
overlooked
in
biomaterials
engineering.
The research
in Dr.
Shazly’s lab
is focused
on defining
and
characterizing
relevant
tissue
properties
for clinical
applications
and
rationally
designing
polymeric
biomaterials
that
leverage
local
biology to
enhance
therapeutic
gain. His
specific
interests
include
physiological
mechanical
testing of
soft matter,
mechanical
modeling,
multiphysics-based
computational
modeling,
tissue-material
adhesion and
tissue
scaffold
engineering.
Education
-
Ph.D.,
Bio- and
Polymeric
Materials
Science
and
Engineering,
Massachusetts
Institute
of
Technology,
2009
-
S.M.,
Materials
Science
and
Engineering,
Massachusetts
Institute
of
Technology,
2007
-
M.S.,
Bioengineering,
Georgia
Institute
of
Technology,
2004
-
B.S.,
Mechanical
Engineering,
Georgia
Institute
of
Technology,
2001
Selected Publications
-
Shazly
T.,
Baker
A.,
Naber
J., Bon
A., Van
Vliet
K., and
Edelman
E.R.,
"Augmentation
of
post-swelling
surgical
sealant
potential
of
adhesive
hydrogels",
Journal
of
Biomedical
Materials
Research
Part A,
Accepted
-
Z.
Kalcioglu
I.,
Qu
M.,
Strawhecker
K.,
Shazly
T.,
Edelman
E.R.,
VanLandingham
M.,
Smith
J., and
Van
Vliet
K,
"Dynamic
and
quasistatic
mechanical
characterization
of
hydrated
biological
tissues
and
tissue
surrogate
gels",
Philosophical
Magazine,
Accepted
-
Artzi
N.*,
Shazly T.*,
Baker
A.,
Ramos
A., and
Edelman
E.R., "Aldehyde-amine
chemistry
enables
modulated
biosealants
with
tissue-specific
adhesion",
Advanced
Materials,
32-33
(2009)
pp
3399-3403
(*Indicates
equal
author
contribution)
-
Baker
A.,
Groothuis
A.,
Jonas
M.,
Ettenson
D.,
Shazly
T.,
Zcharia
E.,
Vlodavsky
I.,
Seifert
P., and
Edelman
E.R.,
"Heparanase
alters
arterial
structure,
mechanics
and
repair
following
endovascular
stenting
in
mice",
Circulation
Research,
104(3):
(2009)
pp.
380-387
-
Artzi
N.,
Shazly
T.,
Crespo
C.,
Ramos
A.,
Chenault
H., and
Edelman
E.R.,
"Characterization
of star
adhesive
sealants
based on
PEG:dextran
hydrogels",
Macromolecular
Bioscience,
9(8),
(2009)
pp
754-765
-
Shazly
T.,
Artzi
N.,
Boehning
F., and
Edelman
E.R,
"Viscoelastic
adhesive
mechanics
of
aldehyde-mediated
soft
tissue
sealants",
Biomaterials, 29
(2008)
pp.
4584-4591
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