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      Dr. Arash Kheradvar

      300 Main Street
      Room A219
      Columbia, SC 29208
      E-mail
      Phone 803.777.3380
      Fax 803.777.0106

       

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    To learn more about the Department of Mechanical Engineering at the University of South Carolina, call or mail us at:

    The University of South Carolina
    Department of Mechanical Engineering
    300 Main Street
    Columbia, SC 29208

    Ph 803.777.4185
    Fax 803.777.0106

    Maps:
    USC campus
    Columbia, SC

Arash Kheradvar

Assistant Professor
Adjunct Assistant Professor of Internal Medicine, Cell and Developmental Biology

Our research focuses on cardiovascular engineering with emphasis on cardiovascular micro/macro mechanics, cardiac imaging and development cardiovascular devices. Gaining fundamental understanding of the governing physics behind the cardiovascular system and developing more systematic tools to better detect and overcome cardiovascular diseases are the major motivations for our research group.

One aspect of our research is focused on techniques that can diagnose diastolic dysfunction much earlier than the current diagnostic techniques using fluid dynamics and in particular vortex dynamics. Another aspect of Dr. Kheradvar’s research is to develop better understanding of ventricular global mechanical properties by characterizing viscoelastic behavior of the heart via different imaging modalities based on experimental methods and modeling techniques.

Dr. Kheradvar’s group is also focused to develop collapsible types of percutaneous heart valves that can be delivered into the heart through small diameter catheters. We are in process of implementing and testing a technology that allows a pre-valve system to be delivered inside the cardiovascular system by an extremely small catheter (3 to 9 French), thus forming a complete heart valve in the designated position.

Education
  • Ph.D., (Bioengineering), California Institute of Technology (Caltech), Pasadena, California (2006)
  • M.D., Tehran University of Medical Sciences, Iran (2000)
Selected Publications
  • A. Kheradvar, M. Gharib, "Influence of ventricular pressure-drop on mitral annulus dynamics through the process of vortex ring formation", Annals of Biomedical Engineering, 35(12), 2050-2064, (2007)
  • A. Kheradvar, Milano M., M. Gharib,, "Correlation between vortex ring formation and mitral annulus dynamics during ventricular rapid filling", ASAIO Journal, 53(1), 8-16, (2007)
  • A. Kheradvar, Milano M., Gorman R.C., Gorman III J.H., M. Gharib, "Assessment of left ventricular viscoelastic components based on ventricular harmonic behavior", Cardiovascular Engineering, 6(1), 30-39, (2006)
  • Gharib M., Rambod E., Kheradvar A., Sahn D., Dabiri J.O., "A global index for heart failure based on optimal vortex formation in the left ventricle", Proceedings of National Academy of Sciences (PNAS), 103(16), 6305-6308, (2006)
  • A. Kheradvar, Kasalko J, Johnson D, M. Gharib, "An in-vitro study of changing profile heights in mitral bioprostheses and their influence on flow", ASAIO Journal, 52(1), 34-38, (2006)
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