Bio-medical engineering

Bio-medical studies :

Cranial suture morphology evolution -- why and how the cranial suture develops from simple, straight line to very complex zig-zag patterns as one matures ?

Effect of drugs (e.g. Granulocyte Colony Stimulating Factor (G-CSF) ) on the change of biological properties of bones, organs, tissue, etc.

Effect of mechanical stimuli on the growth of cranial suture and bones.

Representative Publications

Wu, Yii-Der, Chien, Chi-Hui, Chao, Yuh J., Hill, William D., Yu, Jack, and Li, Xiaodong, “Granulocyte Colony Stimulating Factor (G-CSF) Treatment Alters Femoral Biomechanical Properties in C57BL/6 Mice,” to appear in Journal of Biomedical Materials Research: Part A.
Chien, C.H., Wu, Yii-der and Chao, Y.J., T. Chen, and W.F. Chen, “The Effects of Different Cranial Size on Mechanical Properties of Cranial Suture in Rat and Same-aged Mice,” Strain, to appear.
Wu, Yii-Der, Chien, Chi-Hui, Chao, Yuh J., Yu, Jack C. and Williamson, Mathew, “Fourier Analysis of Human Sagittal Sutures,” The Cleft Palate-Craniofacial Journal, September 2007, Vol.44, No.5, 482-493.
Li, Xiaodong, An, Yuehuei H., Wu, Yii-Der, Song, Ying Ching, Chao, Yuh J., and Chien, Chi-Hui, “A Microindentation Test for Assessing the Mechanical Properties of Cartilaginous Tissues,” Journal of Biomedical Materials Research, Part B, Applied Biomaterials, in press.
Hamrick, Mark W., Ding, Ke-Hong, Pennington1, Catherine, Chao, Yuh J., Wu, Yii-Der, Howard, Boyd, Immel, D., Borlongan, C. M., Paul L., Bollag, W., Walton W. C., Yu, Jack, Isales, Carlos M., “Age-Related Loss of Muscle Mass and Bone Strength in Mice is Associated with a Decline in Physical Activity and Serum Leptin,” Bone, 39 (2006) 845-853.

Representative Publications

Wu, Yii-Der, Chien, Chi-Hui, Chao, Yuh J., Hill, William D., Yu, Jack, and Li, Xiaodong, “Granulocyte Colony Stimulating Factor (G-CSF) Treatment Alters Femoral Biomechanical Properties in C57BL/6 Mice,” to appear in Journal of Biomedical Materials Research: Part A.

Chien, C.H., Wu, Yii-der and Chao, Y.J., T. Chen, and W.F. Chen, “The Effects of Different Cranial Size on Mechanical Properties of Cranial Suture in Rat and Same-aged Mice,” Strain, to appear.

Wu, Yii-Der, Chien, Chi-Hui, Chao, Yuh J., Yu, Jack C. and Williamson, Mathew, “Fourier Analysis of Human Sagittal Sutures,” The Cleft Palate-Craniofacial Journal, September 2007, Vol.44, No.5, 482-493.

Li, Xiaodong, An, Yuehuei H., Wu, Yii-Der, Song, Ying Ching, Chao, Yuh J., and Chien, Chi-Hui, “A Microindentation Test for Assessing the Mechanical Properties of Cartilaginous Tissues,” Journal of Biomedical Materials Research, Part B, Applied Biomaterials, in press.